Original title: Predicting Impacts of Contact Tracing on Epidemiological Inference from Phylogenetic Data Authors: Michael D Kupperman,Ruian Ke,Thomas Leitner This article discusses the importance of robust sampling methods in the field of phylodynamics and explores…
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Original title: ConvexML: Scalable and accurate inference of single-cell chronograms from CRISPR/Cas9 lineage tracing data Authors: Sebastian Prillo,Akshay Ravoor,Nir Yosef,Yun S. Song In this article, the authors discuss the advancements in CRISPR/Cas9 gene editing technology…
Original title: An epigenome-wide analysis of DNA methylation, racialized and economic inequities, and air pollution Authors: Sarah Holmes Watkins,Christian Testa,Andrew J Simpkin,George Davey Smith,Brent Coull,Immaculata De Vivo,Kate Tilling,Pamela D Waterman,Jarvis T Chen,Ana V Diez Roux,Nancy…
Original title: Generating realistic artificial Human genomes using adversarial autoencoders Authors: Callum BURNARD,Alban MANCHERON,William J Ritchie In this article, researchers discuss the challenges and risks associated with publicly available human genomes and propose a novel…
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Original title: Minimizing Reference Bias with an Impute-First Approach Authors: Naga Sai Kavya Vaddadi,Taher Mun,Ben Langmead In this article, the authors discuss a new approach called the impute-first alignment framework, which aims to reduce reference…
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Original title: External validation of machine learning models – registered models and adaptive sample splitting Authors: Giuseppe Gallitto,Robert Englert,Balint Kincses,Raviteja Kotikalapudi,Jialin Li,Ulrike Bingel,Tamas Spisak This article discusses the challenges of predictive modeling in the field…
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Original title: ξ-π: a nonparametric model for neural power spectra decomposition Authors: Shiang Hu,Zhihao Zhang,Xiaopei Wu,Pedro A. Valdes-Sosa This article discusses the challenge of accurately analyzing the power spectra of brain activity. The power spectra…
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Original title: Molecular dynamics simulations provide insights into ULK-101 potency and selectivity toward autophagic kinases ULK1/2 Authors: Robert M. Vaughan,Bradley M. Dickson,Katie R. Martin,Jeffrey P. MacKeigan In this article, the researchers focused on understanding how…
Original title: Towards modeling genome-scale knowledge in the global ocean Authors: Antoine Regimbeau,Olivier Aumont,Chris Bowler,Lionel Guidi,George A Jackson,Eric Karsenti,Laurent Memery,Alessandro Tagliabue,Damien Eveillard This article discusses the limitations of Earth System Models (ESMs) in accurately representing…
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Original title: Healthy microbiome – moving towards functional interpretation Authors: Kinga Zielinska,Witold Rudnicki,Tomasz Kosciolek,Pawel Piotr Labaj In this article, the authors discuss the potential of using microbiome-based disease detection approaches as diagnostic options for various…
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