Can Adaptive Tri-Factor Non-Negative Matrix Factorization deconvolute cell types?

Original title: Adaptive Regularized Tri-Factor Non-Negative Matrix Factorization for Cell Type Deconvolution Authors: Tianyi Liu,Quefeng Li,Xiaojing Zheng,Fei Zou In this article, the authors discuss the importance of accurately identifying different cell types from bulk gene…

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What is uniLIVER and why is it important for mapping cellular states?

Original title: uniLIVER: a Human Liver Cell Atlas for Data-Driven Cellular State Mapping Authors: Yanhong Wu,Yuhan Fan,Yuxin Miao,Yuman Li,Zeyu Chen,Guifang Du,Jinmei Diao,Yu-Ann Chen,Mingli Ye,Renke You,Amin Chen,Yixin Chen,Wenrui Li,Wenbo Guo,Jiahong Dong,Xuegong Zhang,Yunfang Wang,Jin Gu In this…

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Can population-level analysis be done using only HiFi and Hi-C data for reference-guided automatic assembly of genomic tandem repeats?

Original title: Reference-guided automatic assembly of genomic tandem repeats with only HiFi and Hi-C data enables population-level analysis Authors: Huaming Wen,Weihua Pan In this article, the researchers address the limitations of current methods for complete…

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How can computational pathology be democratized for The Cancer Genome Atlas with optimized Whole Slide Image representations?

Original title: Democratizing computational pathology: optimized Whole Slide Image representations for The Cancer Genome Atlas Authors: Tristan Lazard,marvin Lerousseau,Sophie Gardrat,Anne Vincent-Salomon,Marc-Henri Stern,Manuel Rodrigues,Etienne Decenciere,Thomas Walter In this article, the authors discuss the potential of using…

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How can we infer environment-dependent microbial interactions using kinetics?

Original title: Kinetics-based Inference of Environment-Dependent Microbial Interactions and Their Dynamic Variation Authors: Hyun-Seob Song,Na-Rae Lee,Aimee K. Kessell,Hugh C. McCullough,Seo-Young Park,Kang Zhou,Dong-Yup Lee In this article, the authors address the need for a better understanding…

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How can computational methods be benchmarked for identifying variable genes and peaks?

Original title: Benchmarking computational methods to identify spatially variable genes and peaks Authors: Zhijian Li,Zain M.Patel,Dongyuan Song,Guanao Yan,Jingyi Jessica Li,Luca Pinello This article explores the field of spatially resolved transcriptomics, which allows scientists to examine…

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Can Pyramid Vision Transformer Detect Alzheimer’s Disease in White Matter of MRI Data?

Original title: PVTAD: ALZHEIMERS DISEASE DIAGNOSIS USING PYRAMID VISION TRANSFORMER APPLIED TO WHITE MATTER OF T1-WEIGHTED STRUCTURAL MRI DATA Authors: Maryam Akhavan Aghdam,Serdar Bozdag,Fahad Saeed In this article, researchers discuss the importance of timely diagnosis…

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How can graph attention networks help identify new disease genes by integrating multiple gene interaction networks and omics data?

Original title: Integration of multi-source gene interaction networks and omics data with graph attention networks to identify novel disease genes Authors: Kaiyuan Yang,Jiabei Cheng,Shenghao Cao,Xiaoyong Pan,Hong-bin Shen,Cheng Jin,Ye Yuan In this article, the authors discuss…

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