What is the model for telomere length dynamics across generations?

Original title: A branching model for intergenerational telomere length dynamics

Authors: Athanasios Benetos (DCAC, CHRU Nancy), Olivier Coudray, Anne Gégout-Petit (IECL, BIGS), Lionel Lenôtre (IRIMAS, ARCHIMEDE, PASTA), Simon Toupance (DCAC), Denis Villemonais (IECL, BIGS, IUF)

In this article, the author focuses on understanding the evolution of telomere length in a population across multiple generations. They develop a model that looks at the individual level and incorporates factors such as gamete mean telomere length and age. By using this model, they are able to study how telomere length evolves over time and its impact on population growth.

The article also explores the Malthusian behavior of the model and conducts numerical simulations to better understand the effect of different parameters on telomere length evolution. This research is important for understanding the biological aspects of telomeres and how they contribute to the overall health and vitality of a population.

By studying telomere length in this way, the article offers valuable insights into the factors that influence telomere evolution and provides a foundation for further research in this field.

Original article: https://arxiv.org/abs/2311.09678